Cycloaddition of furfurylamines to maleic anhydride and its substituted derivatives

The regio- and stereoselectivity of the [4+2] cycloaddition of maleic, citraconic, dichloromaleic, and dibromomaleic anhydrides to difurfuryl amines and secondary furfurylamines were studied. N-Furfuryl-, N-phenyl-, and N-benzylhexahydrooxoepoxyisoindole-7-carboxylic acids were synthesized. An approach was developed for obtaining hexahydroepoxyoxoisoindole-7-carboxylic acid unsubstituted at the nitrogen atom. Aromatization of the oxabicycloheptene fragment of the dihaloepoxyiso-indolonecarboxylic acids gave a series of 7-carboxy-2-R-isoindol-1-ones. © 2012 Springer Science+Business Media, Inc.

Editors
-
Publisher
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Number of issue
3
Language
English
Pages
505-513
Status
Published
Department
-
Number
-
Volume
48
Year
2012
Organizations
  • 1 Peoples' Friendship University of Russia, 6 Miklukho-Maklaya St, Moscow 117198, Russian Federation
Keywords
Furfurylamines; Isoindolones; Maleic anhydride
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/2388/