Glucosaminyl muramy ldipeptide in treatment and prevention of infectious diseases

Infectious diseases and their spread make a challenge to actualize immunoprophylaxis and immunotherapy in order to increase the reserves of the immune system in forming an adequate response to the pathogen. Numerous studies by clinicians and fundamental scientists are devoted to finding an effective solution to this problem. An example of the successful use of these advances in the treatment and prevention of infectious diseases is the use of glucosaminyl muramyl dipeptide (GMDP), which specifically activates NOD2-receptors, responsible for the realization of innate and acquired immunity. The review provides examples of the complex use in practical medicine of the drug Liñopid based on GMDP for the treatment of infectious diseases. The main schemes of immunoprophylaxis and immunotherapy of diseases of bacterial and viral etiology with the help of muramyl dipeptide of different age groups are highlighted. Particular attention is paid to the possibility of using GMDP for specific prophylaxis of viral infections. © 2021 Nutritec. All rights reserved.

Авторы
Guryanova S.V. 1, 2 , Khaitov R.M.3, 4
Номер выпуска
3
Язык
Русский
Страницы
79-86
Статус
Опубликовано
Том
9
Год
2020
Организации
  • 1 Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, 117997, Russian Federation
  • 2 Peoples' Friendship University of Russia (RUDN University), Medical Institute, Moscow, 117198, Russian Federation
  • 3 National Research Center, Institute of Immunology, Federal Medical Biological Agency, Moscow, 115522, Russian Federation
  • 4 A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Ministry of Healthcare of the Russian Federation, Moscow, 127473, Russian Federation
Дата создания
16.12.2021
Дата изменения
16.12.2021
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/76398/
Поделиться

Другие записи