Damaging effects of lyticase on candida albicans and changes in the response of rat alveolar macrophages to the contact with yeast-like fungi

Changes in the cell wall of yeast-like fungi Candida albicans caused by bacterial enzyme lyticase were studied under an electron microscope. The results were compared with the findings on phagocytosis of lyticase-treated Candida albicans by rat alveolar macrophages. It was shown that destruction of the mannan and fibrous outer layers of the cell wall of yeast-like fungi treated with the enzyme led to the release of intracellular organelles and their content. Lyticase treatment reduced the resistance of Candida albicans to intracellular digestion by macrophages contributing to completion of phagocytosis. © 2011 Springer Science+Business Media, Inc.

Авторы
Издательство
New York Consultants BureauSpringer / Автономная некоммерческая организация Издательство Российской академии медицинских наук
Номер выпуска
6
Язык
Английский
Страницы
705-708
Статус
Опубликовано
Том
151
Год
2011
Организации
  • 1 M. P. Chumakov Institute of Poliomyelitis and Viral Encephalites, Russian Academy of Medical Sciences, Moscow region, Russian Federation
  • 2 Department of Microbiology and Virology, People's Friendship University of Russia, Moscow, Russian Federation
Ключевые слова
Candida albicans; lyticase; phagocytosis; rat alveolar macrophages; yeast-like fungi
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/2493/