Occult form of premature ovarian insufficiency

Premature ovarian insufficiency (POI) is a life-changing diagnosis, with profound physical and psychological consequences. Despite the description of different genetic, immune and iatrogenic factors of POI, the etiology of most cases of this disease are unexplained, and optimal management strategies are still unclear. Recent data showed that POI may have a long period of oligomenorrhea before the fully developed form (complete ovarian failure stage), with the occurrence of amenorrhea and climacteric symptoms. The main problem in the recognition of early stages of POI is the lack of proper diagnostic criteria. Patients with an undiagnosed occult form of POI may present with menstrual irregularities, unexplained infertility or repeated IVF failures. We evaluated 23 patients with unexplained oligomenorrhea and/or infertility. After a proper evaluation of these patients, a low ovarian reserve was identified, and an occult form of POI was diagnosed. © 2016 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Editors
-
Publisher
-
Number of issue
-
Language
English
Pages
30-32
Status
Published
Department
-
Number
-
Volume
32
Year
2016
Organizations
  • 1 Department of Obstetrics and Gynecology with Course of Perinatology of the Russian University of Peoples' Friendship, Moscow, Russian Federation
Keywords
Amenorrhea; antral follicle count (AFC); infertility; occult premature ovarian insufficiency; oligomenorrhea; ovarian reserve; premature menopause; premature ovarian failure; premature ovarian insufficiency (POI)
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/3805/