Tandem Michael addition - Hoffman elimination sequence of DMAD on tetrahydropyrrolo[3,2-c]pyridines. New route to vinylpyrroles

The reaction of tetrahydropyrrolo[3,2-c]pyridines with DMAD in THF at room temperature results in piperidine ring cleavage producing α- or β-vinylpyrroles in moderate to good yields. The resulting compounds are hardly available by other synthetic means and are good candidates for further transformations.

Publisher
Freund Publishing House Ltd
Number of issue
5
Language
English
Pages
461-466
Status
Published
Volume
7
Year
2001
Organizations
  • 1 Organic Chemistry Department, Russ. Peoples Friendship University, 6, Mikluho-Maklaia St., Moscow, 117198, Russian Federation
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/357/
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