Dynamics of Holter electrocardiogram monitoring in patients with chronic heart failure and atrial fibrillation on the background of cardiac contractility modulation [Динамика показателей холтеровского мониторирования электрокардиограммы у пациентов с хронической сердечной недостаточностью и фибрилляцией предсердий на фоне модуляции сердечной сократимости]

Aim. To evaluate the dynamics of cardiac arrhythmias on the background of cardiac contractility modulation (MCC) in patients with chronic heart failure (CHF) and various forms of atrial fibrillation (AF) on the basis of daily electrocardiogram (ECG) monitoring. Materials and methods. In 100 patients with CHF and AF, the following studies were performed before implantation of the MCC device and after 12 months of follow-up: 12-channel ECG with an estimate of the width of the QRS complex, transthoracic echocardiography (EchoCG), and Holter ECG monitoring. All patients received long-term optimal drug therapy for CHF before surgery. Results. The results obtained indicate that there is no effect of MCC on the development and progression of ventricular arrhythmias in patients with CHF and AF during the year of follow-up, both extrasystole and tachyarrhythmias, regardless of the etiology and LVEF (less than 35% or more than 35%), and a decrease in the frequency of AF paroxysms in patients with CHF during treatment. These results are due to the reverse remodeling of the LV myocardium under the influence of the MCC device. Conclusion. The use of MСС in patients with CHF and AF is a safe method of therapy that does not induce cardiac arrhythmias, including ventricular extrasystole. Large-scale comparative studies are required to evaluate these results. © 2021 Consilium Medikum. All rights reserved.

Safiullina A.A.1 , Uskach T.M.1, 2 , Sharapova Y.S.1 , Kochetov A.G. 3, 4 , Sapelnikov O.V.1 , Tereshchenko S.N. 1, 2
Номер выпуска
  • 1 National Medical Research Center of Cardiology, Moscow, Russian Federation
  • 2 Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation
  • 3 People’s Friendship University of Russia (RUDN University), Moscow, Russian Federation
  • 4 Institute of Laboratory Medicine, Moscow, Russian Federation
Ключевые слова
Atrial fibrillation; Cardiac contractility modulation; Heart failure; Holter ECG monitoring; QRS complex; Ventricular extrasystole
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