Oxidative coupling and unusual hydroxymethylation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the presence of dicyanomethane

Potassium permanganate oxidizes a mixture of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (THP) 1 and dicyanomethane to 2-dicyanomethylidenetetrahydropyridine 2, but using manganese dioxide leads to the unusual oxidative hydroxymethylation of 1; subsequent treatment of the 3-hydroxymethyltetrahydropyridine 4 formed with aqueous potassium permanganate results in lactamination, accompanied by aromatization or oxodihydroxylation.

Авторы
Soldatenkov A.T. 1 , Temesgen A.W. 1 , Kuleshova L.N.2 , Khrustalev V.N.2
Редакторы
-
Издательство
Royal Society of Chemistry
Номер выпуска
5
Язык
Английский
Страницы
193-195
Статус
Опубликовано
Подразделение
-
DOI
-
Номер
-
Том
8
Год
1998
Организации
  • 1 Peoples' Friendship University of Russia, 117198 Moscow, Russian Federation
  • 2 A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 117813 Moscow, Russian Federation
Ключевые слова
-
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/640/