Alzheimer's disease: Beta amyloid and lipid metabolism

Amyloid deposits found in brains of Alzheimer's disease, Down's syndrome and normal aged individuals are composed mainly of aggregated amyloid beta (Ab), soluble form which is a normal protein. We previously reported that soluble Ab (sAb) in normal human plasma and cerebrospinal fluid is complexed to high density lipoprotein (HDL). Consequences of sAb association with the HDL and Ab involvement in the lipid turnover are discussed herein.

Авторы
Koudinova N.V.1 , Berezov T.T. 1, 2 , Koudinov A.R.1
Редакторы
-
Издательство
-
Номер выпуска
1
Язык
Русский
Страницы
32-34
Статус
Опубликовано
Подразделение
-
DOI
-
Номер
-
Том
44
Год
1998
Организации
  • 1 Russian Academy of Medical Sciences, Department of Biochemistry, School of Medicine, Mikluho-Maklay St. 8, Moscow 117198, Russian Federation
  • 2 Russ. Peoples' Friendship University, Mikluho-Maklay St. 8, Moscow 117198, Russian Federation
Ключевые слова
Alzheimers disease; Amyloid beta; Lipids; Lipoproteins
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/624/