Alzheimer's disease: Beta amyloid and lipid metabolism

Amyloid deposits found in brains of Alzheimer's disease, Down's syndrome and normal aged individuals are composed mainly of aggregated amyloid beta (Ab), soluble form which is a normal protein. We previously reported that soluble Ab (sAb) in normal human plasma and cerebrospinal fluid is complexed to high density lipoprotein (HDL). Consequences of sAb association with the HDL and Ab involvement in the lipid turnover are discussed herein.

Authors
Koudinova N.V.1 , Berezov T.T. 1, 2 , Koudinov A.R.1
Number of issue
1
Language
Russian
Pages
32-34
Status
Published
Volume
44
Year
1998
Organizations
  • 1 Russian Academy of Medical Sciences, Department of Biochemistry, School of Medicine, Mikluho-Maklay St. 8, Moscow 117198, Russian Federation
  • 2 Russ. Peoples' Friendship University, Mikluho-Maklay St. 8, Moscow 117198, Russian Federation
Keywords
Alzheimers disease; Amyloid beta; Lipids; Lipoproteins
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/624/
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