Preparation and Investigation of Tabletted Medicinal Formulations of a Solid Dispersion of Rutin

Asolid dispersion of rutin based on polyvinylpyrrolidone had greater solubility than rutin substance, which is valuable for creating effective formulations based on this material. We describe here the preparation of tableted medicinal formulations of a solid dispersion of rutin prepared by direct pressing and moist granulation. A comparative analysis of the resulting granulates and tablets in terms of the main physical-technical characteristics is presented. © 2015, Springer Science+Business Media New York.

Авторы
Krasnyuk I.I.Jr. , Koval’skii I.V.1 , Nikulina O.I.1 , Belyatskaya A.V.1 , Krasnyuk I.I.1 , Kharitonov Y.Y.1 , Grikh V.V.1 , Korol’ L.A.1 , Obidchenko Y.A. 2 , Vorob’ev A.N.2
Редакторы
-
Издательство
-
Номер выпуска
7
Язык
Английский
Страницы
481-485
Статус
Опубликовано
Подразделение
-
Номер
-
Том
49
Год
2015
Организации
  • 1 First I. M. Sechenov Moscow State Medical University, Ministry of Health of the Russian Federation, Moscow, Russian Federation
  • 2 Collaborative Resource Center (Scientific and Educational Center), Russian University of the Friendship of the Peoples, Moscow, Russian Federation
Ключевые слова
mechanism of action; properties; rutin; rutin aglycone
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/4500/