Multicomponent Synthesis of 4-Alkyl(Aryl, Hetaryl)-2-alkoxycarbonyl(aroyl, carbamoyl)- 3,6-diamino-5-cyanothieno[2,3-b]pyridines

The condensation of malononitrile with hydrogen sulfide and aldehydes in the presence of triethylamine in ethanol at room temperature afforded 4-alkyl(aryl, hetaryl)-2,6-diamino-3,5-dicyano-4H-thiopyrans. Treatment of the latter in situ with alkali in DMF, followed by addition of an alkylating agent, led to the formation of 4-alkyl(aryl, hetaryl)-2-alkoxycarbonyl(aroyl, carbamoyl)-3,6-diamino-5-cyanothieno[2,3-b]- pyridines. © 2018, Pleiades Publishing, Ltd.

Авторы
Dyachenko I.V.1 , Dyachenko V.D.1 , Dorovatovskii P.V. 2 , Khrustalev V.N. 2, 3 , Nenajdenko V.G. 4
Номер выпуска
10
Язык
Английский
Страницы
1435-1445
Статус
Опубликовано
Том
54
Год
2018
Организации
  • 1 Taras Shevchenko Lugansk National University, ul. Oboronnaya 2, Lugansk, 91000, Ukraine
  • 2 National Research Center “Kurchatov Institute,”, pl. Akademika Kurchatova 1, Moscow, 123182, Russian Federation
  • 3 Peoples’ Friendship University of Russia, ul. Miklukho-Maklaya 6, Moscow, 117198, Russian Federation
  • 4 Faculty of Chemistry, Moscow State University, Leninskie gory 1, Moscow, 119991, Russian Federation
Дата создания
04.02.2019
Дата изменения
04.02.2019
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/36300/