Blood-testis barrier after transplantation of pituitary cell into dystopic testicle
A total of 87 allotransplantations of the pituitary were carried out: into intact testicle with or without subsequent transposition into the abdominal cavity and on a previously created model of unilateral cryptorchidism. Histological study showed that pituitary cells retained viability for up to 3 months in all three series. The main structures of the blood-testis barrier (membranes of testicular tubules, tunica albuginea testis, vascular walls, and interstitial tissue) were not damaged, which determined advantages of dystopic testicle in pituitary cell allotransplantation.
1 Research and Clinical Center of Andrology and Endocrine Organ Transplantation, Department of Operative Surgery and Surgical Anatomy, Russian University of Peoples' Friendship, Moscow, Russian Federation