Allotransplantation of pituitary cells to rat testicle
Fifty-three transplantations of pituitary tissue (intact and minced with scissors) under the tunica albuginea testis were carried out. In both series pituitary cells retained viability for up to 6 months. Transplantation of cell suspension was not accompanied by the formation of necrotic zone in the transplant; the adjacent testicular tubules and the entire testicular structure remained unchanged, while transplantation of large fragments of the pituitary tissue impaired of spermatogenesis in the adjacent testicular tubules, although most of them remained unchanged. Hence, cell suspension is preferable for transplantation of pituitary tissue into the testicle.
1 Research and Clinical Center of Andrology and Transplantation of Endocrine Organs, Department of Operative Surgery and Surgical Anatomy, Russian University of Peoples' Friendship, Moscow, Russian Federation
Бюллетень экспериментальной биологии и медицины
Клеточные технологии в биологии и медицине.
New York Consultants BureauSpringer / Автономная некоммерческая организация Издательство Российской академии медицинских наук.