The study of immunological component in antitumor effect of Trypanosoma cruzi

The experiments with passive transfer of splenocytes obtained from animals immunized with Trypanosoma cruzi lysate revealed the role of cell-mediated component of the immunity in the antitumor effect of T. cruzi. The common features of T. cruzi antigens and tumor-specific antigens of Ehrlich's adenocarcinoma were demonstrated. These antigens were shown to have common epitopes with mammalian mucins. The oncoprotective effect was achieved by immunization with type II and III mucins and was reproduced after passive transfer of splenocytes from immunized animals. © Springer Science+Business Media, Inc. 2008.

Авторы
Zenina A.V.1 , Kravtsov E.G. 1 , Tsetsegsaikhan B.1 , Yashina N.V. 1 , Dalin M.V. 1 , Karpenko L.P. 1 , Sheklakova L.A. 1 , Kallinikova V.D. 2
Редакторы
-
Издательство
New York Consultants BureauSpringer / Автономная некоммерческая организация Издательство Российской академии медицинских наук
Номер выпуска
3
Язык
Английский
Страницы
352-354
Статус
Опубликовано
Подразделение
-
Номер
-
Том
145
Год
2008
Организации
  • 1 Department of Microbiology, Russian University of People Friendship, Moscow, Russian Federation
  • 2 Invertebrate Physiology Department, M. V. Lomonosov Moscow State University, Moscow, Russian Federation
Ключевые слова
Antitumor activity; Ehrlich's adenocarcinoma; Immunocompetent cells; Trypanosoma cruzi
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/3063/