(6aS*,6bS*,11R*,11aR*)-6-(2-Furylmethyl)-5, 12-dioxo-5,6,6a,6b,7,11,11a,12-octahydrofuro[3′,2′:5,6]isoindolo[2, 1-a]quinazoline-11-carboxylic acid

The title compound, C23H18N2O6, is the product of an intra-molecular thermal cyclo-addition within 1-malein-2-[(E)-2-(2-fur-yl)vin-yl]-4-oxo-3,4-dihydro-quinazoline. The mol-ecule comprises a previously unknown fused penta-cyclic system containing two five-membered rings (2-pyrrolidinone and furan) and three six-membered rings (benzene, 2,3-dihydro-4-pyrimidinone and dihydro-cyclo-hexa-ne). The central five-membered pyrrolidinone ring has the usual envelope conformation. The six-membered dihydro-pyrimidinone and dihydro-cyclo-hexane rings adopt a half-boat and a half-chair conformation, respectively. The dihedral angle between the planes of the terminal benzene and furan rings is 45.99 (7)°. In the crystal, O - H⋯O hydrogen bonds link the mol-ecules into centrosymmetric dimers. Weak C - H⋯O hydrogen bonds consolidate further the crystal packing, which exhibits π-π inter-actions, with a short distance of 3.556 (3) Å between the centroids of benzene rings of neighbouring mol-ecules. © Obushak et al. 2011.

Авторы
Obushak M.D.1 , Horak Y.I.1 , Zaytsev V.P. 2 , Motorygina E.L. 2 , Zubkov F.I. 2 , Khrustalev V.N.3
Номер выпуска
11
Язык
Английский
Страницы
o3031-o3032
Статус
Опубликовано
Том
67
Год
2011
Организации
  • 1 Department of Organic Chemistry, Ivan Franko National University of Lviv, 6 Kyryla i Mefodiya Street, Lviv 79005, Ukraine
  • 2 Organic Chemistry Department, Russian Peoples Friendship University, Miklukho-Maklaya Street 6, Moscow, 117198, Russian Federation
  • 3 X-ray Structural Centre, A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 Vavilov Street, B-334, Moscow 119991, Russian Federation
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/2478/
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