Integral approach to evaluation of the pathogenic activity of trypanosoma cruzi clones as exemplified by the mexican strain

Comparative histopathological study and analysis of parasite load in different muscle groups were carried out in BALB/c mice during the acute phase of Chagas disease. Activities of C104 clone of T. cruzi strain TPAP/MX/2002/Albarrada and the parental strain were compared. Panoramic 2D-microscopy imaging of sample surface was used and quantitative analysis of parasitism and pathologic damage was performed. The infection rates in various muscle groups were as follows: myocardium = abdominal muscles = lumbar muscles = femoral muscles ← diaphragm for the clone and myocardium⊠£abdominal muscles = lumbar muscles = femoral muscles → diaphragm for the parental strain. © 2013 Springer Science+Business Media New York.

Авторы
Melnikov V.1 , Espinoza-Gomez F.1 , Newton-Sanchez O.1 , Delgado-Ensiso I.1 , Montesinos-Lopez O.A.2 , Dalin M.V. 3 , Espinoza B.4 , Martinez I.4 , Sheklakova L.A. 3 , Dobrovinskaya O.5 , Karpenko L.P. 3
Редакторы
-
Издательство
New York Consultants BureauSpringer / Автономная некоммерческая организация Издательство Российской академии медицинских наук
Номер выпуска
1
Язык
Английский
Страницы
70-72
Статус
Опубликовано
Подразделение
-
Номер
-
Том
156
Год
2013
Организации
  • 1 Medical Faculty, Moscow, Russian Federation
  • 2 Faculty of Telematics, University of Colima, Colima, Mexico
  • 3 Medical Faculty, Russian University of Peoples' Friendship, Moscow, Russian Federation
  • 4 Departamento de Immunologia Instituto de Investigaciones Biomédicas, UNAM (U.N.A.M.), Mexico D. F., Mexico
  • 5 Center of Biomedical Investigations, University of Colima, Colima, Mexico
Ключевые слова
diaphragm; muscle tissue tropism; myocardium; myositis; Trypanosoma cruzi
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/1973/