Перампанел в дополнительной терапии фокальных и первично-генерализованных тонико-клонических приступов у детей 4–12 лет: клинические данные, опыт применения и практические рекомендации

Perampanel in the additional therapy of focal and primary generalized tonic-clonic seizures in children 4–12 years old: clinical data, experience of use and practical recommendations

On March 18, 2021, an online council of experts in the field of epilepsy treatment was held, dedicated to the use of perampanel in the additional therapy of focal seizures (FS) and primary generalized tonic-clonic seizures (PGTCS) in children 4–12 years old. During the event, the features of the use of perampanel in this group of patients were discussed, considering the specifics of everyday clinical practice, current possibilities of PGTCS and FS therapy in children, its goals, as well as unsolved problems in the treatment of pediatric patients with PGTCS and FS. Particular attention was paid to the role of perampanel in the treatment of PGTCS and FS in children and its effectiveness in specific types of focal seizures. © 2021 IRBIS LLC. All rights reserved.

Authors
Mukhin K.Yu.1 , Belousova E.D.2 , Burd S.G.2 , Barkhatov M.V.3 , Ermolenko N.А.4 , Zyryanov S.К. 5, 6 , Karpovich E.I.7 , Morozova E.А.8 , Odintsova G.V.9
Journal
Эпилепсия и пароксизмальные состояния
Number of issue
2
Language
Russian
Pages
180-187
Status
Published
Link
External link
DOI
10.17749/2077-8333/EPI.PAR.CON.2021.087
Volume
13
Year
2021
Organizations
  • 1 St. Luke Institute of Pediatric Neurology and Epilepsy, 9 Academician Anokhin Str., Moscow, 119571, Russian Federation
  • 2 Pirogov Russian National Research Medical University, 1 Ostrovityanov Str., Moscow, 117997, Russian Federation
  • 3 Federal Siberian Scientific and Clinical Center, Federal Medical and Biological Agency of Russia, 26 Kolomenskaya Str., Krasnoyarsk, 660037, Russian Federation
  • 4 Voronezh Regional Clinical Hospital No. 1, 151 Moskovskiy Prospect, Voronezh, 394068, Russian Federation
  • 5 Peoples’ Friendship University of Russia, 8 corp. 2 Miklukho-Maklay Str., Moscow, 117198, Russian Federation
  • 6 City Clinical Hospital No. 24, 10 Pistsovaya Str., Moscow, 127015, Russian Federation
  • 7 Nizhny Novgorod Semashko Regional Clinical Hospital, 190 Rodionov Str., Nizhny Novgorod, 603126, Russian Federation
  • 8 Kazan State Medical Academy, Branch of Russian Medical Academy of Continuing Professional Education, 11 Mushtari Str., Kazan, 420012, Russian Federation
  • 9 Almazov National Medical Research Center, 2 Akkuratov Str., Saint Petersburg, 197341, Russian Federation
Keywords
Children; Clinical practice; Epilepsy; Focal seizures; Perampanel; Primary generalized tonic-clonic seizures; Quality of life; Therapy features
Date of creation
16.12.2021
Date of change
16.02.2022
Short link
https://repository.rudn.ru/en/records/article/record/77108/
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