New method for the synthesis of 4-spirocyclopentane- and 4-spirocyclohexanenicotinic acid nitriles and amides

The multicomponent condensation of cyclopentylidene- or cyclohexylidenemalononitrile, cyanoacetic acid amides or thioamides, and alkylating agents affords 4-spirocyclopentane- and 4-spirocyclohexanenicotinic acid nitriles and amides. The structures of several reaction products were determined by X-ray diffraction. © 2021, Springer Science+Business Media LLC.

Authors
Dyachenko I.V.1 , Dyachenko V.D.1 , Dorovatovskii P.V. 2 , Khrustalev V.N. 3, 4 , Nenajdenko V.G. 5
Journal
Russian Chemical Bulletin
Number of issue
5
Language
English
Pages
949-959
Status
Published
Link
External link
DOI
10.1007/s11172-021-3172-9
Volume
70
Year
2021
Organizations
  • 1 Lugansk State Pedagogical University, 2 ul. Oboronnaya, Lugansk, 91011, Ukraine
  • 2 National Research Center “Kurchatov Institute”, 1 ul. Akad. Kurchatova, Moscow, 123182, Russian Federation
  • 3 Peoples’ Friendship University of Russia (RUDN University), 6 ul. Miklukho-Maklaya, Moscow, 117198, Russian Federation
  • 4 N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp., Moscow, 119991, Russian Federation
  • 5 Lomonosov Moscow State University, 1 Leninskie Gory, Moscow, 119991, Russian Federation
Keywords
4-spirocyclopentane- and 4-spirocyclohexanenicotinic acid amides and nitriles; alkylation; multicomponent condensation; X-ray diffraction
Date of creation
20.07.2021
Date of change
20.07.2021
Short link
https://repository.rudn.ru/en/records/article/record/74304/
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