Results of ex vivo investigation of new ophthalmic solution for riboflavin-uv-absorbance induced cross-linking of thin corneas

The effectiveness of corneal riboflavin saturation through instillation of solutions for UV cross-linking was studied in ex vivo experiments on porcine eyes. In addition, the effect of solutions on the comea thickness was studied and a new ophthalmological agent containing riboflavin and chitosan succinate for UV absorbance-induced collagen cross-linking of thin corneas was proposed. © 2018 Izdatel'stvo Meditsina. All rights reserved.

Authors
Khalimov A.R. 1 , Kataev V.A. 2 , Drozdova G.A. 3 , Kazakbaeva G.M. 1 , Khalikov R.A. 2
Journal
Experimental and Clinical Pharmacology
Issue number
2
Language
Russian
Pages
30-32
State
Published
Link
External link
DOI
10.30906/0869-2092-2018-81-2-30-32
Volume
81
Year
2018
Organizations
  • 1 Ufa Eye Research Institute, Academy of Sciences of the Republic of Bashkortostan, Ufa, ul. Pushkina 90, Ufa, Bashkortostan, 450008, Russian Federation
  • 2 Bashkir State Medical University, ul. Lenina 3, Ufa, Bashkortostan, 450000, Russian Federation
  • 3 Peoples Friendship University of Russia, ul. Miklukho-Maklaya 6, Moscow, 117198, Russian Federation
Keywords
Chitosan; Cornea; Keratoconus; Riboflavin; Uv-absorbance-induced cross-linking
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