Oxidation reactions of azines. 10. Synthesis, structure, and oxodihydroxylation of 3-hydroxymethyl-1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

It has been established that oxidation of a mixture of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and dicyanomethane or formaldehyde with manganese dioxide gives 3-hydroxymethyl-1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, the structure of which was confirmed by X-ray structural analysis. Some oxidative conversions by potassium permanganate of the product formed and its esters have been studied. These included lactamization, aromatization, and oxodihydroxylation.

Publisher
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Number of issue
4
Language
English
Pages
471-477
Status
Published
Volume
39
Year
2003
Organizations
  • 1 Russ. People's Friendship University, Moscow 117198, Russian Federation
Keywords
Hydroxymethylation; Oxidation; Oxodihydroxylation; Polyhydroxypiperidin-2-ones; Tetrahydropyridines
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/68/