Intramolecular cyclization of gem-benzylaminoallylcyclohexane under the action of sulfuric acid

When treated with 85% sulfuric acid at 85°C, gem-benzylaminoallylcyclohexane is converted to spiro[tetrahydrobenz-2-azepine-3-cyclohexane], while at 20°C or in boiling chloroform 3,4,5,6-tetrahydro-3-benzyl-6-methylspiro[1,2,3-oxathiazine-2,2-dioxide-4- cyclohexane] is formed as the major product. The second compound is cleaved by alcohol solution of alkali to 1-benzyl-4-methylspiro[azetidine-2-cyclohexane]. ©1999 KluwerAcademic/Plenum.

Authors
Publisher
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Number of issue
2
Language
English
Pages
199-203
Status
Published
Volume
35
Year
1999
Organizations
  • 1 Russian University of International Friendship, Moscow 117198, Russian Federation
  • 2 School of Chemistry, Industrial University of Santander, Bucaramanga, A. A. 678, Colombia
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/593/
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