Cortical control of nociceptive transmission from the heart

Depriming effect of the cerebral cortex (predominantly of zones 1 and 2 of viscerosomatic sensitivity) on transmission of the cardiac afferent signals with a subcortical nociceptive component, which were provoked by electrical stimulation of the sinoatrial node of the heart conduction system, was established in experiments on cats. The agonist of opiate M-receptors morphine considerably potentiated the effect of cortical stimulation, while opiate receptor blocker naloxone antagonized it.

Authors
Editors
-
Publisher
New York Consultants BureauSpringer / Автономная некоммерческая организация Издательство Российской академии медицинских наук
Number of issue
12
Language
English
Pages
1206-1208
Status
Published
Department
-
DOI
-
Number
-
Volume
128
Year
1999
Organizations
  • 1 Department of Pharmacology, Therapeutic, and Medical Prophylactic Faculties, I. M. Sechenov Moscow Medical Academy, Moscow, Russian Federation
  • 2 Department of Pathological Physiology, Russian University of Peoples' Friendship, Moscow, Russian Federation
Keywords
Cerebral cortex; Descending control; Heart; Nociception
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/521/