Proportional criterion of metabolic activity and fundamentals of drug dosage

A method for determining the drug dose is proposed, according to which the dose of injected drug is proportional to body weight to the power 2/3. The dosage of narcotic analgesic ketamine is in good agreement with the proposed relationship.

Authors
Turkovskii I.I. 1, 2 , Kuznetsov A.N. 1, 2
Journal
Бюллетень экспериментальной биологии и медицины\r\nКлеточные технологии в биологии и медицине (Bulletin of Experimental Biology and Medicine)
Publisher
New York Consultants BureauSpringer / Автономная некоммерческая организация Издательство Российской академии медицинских наук
Issue number
5
Language
English
Pages
466-467
State
Published
Link
External link
DOI
10.1007/BF02439804
Volume
129
Year
2000
Organizations
  • 1 Military Medical Academy, St. Petersburg, Russian Federation
  • 2 Russian University of Peoples' Friendship, Moscow, Russian Federation
Keywords
Body surface area; Dosage; Metabolic activity; Narcosis
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