Efficacy of ozeltamivir (Tamiflu™) in adult influenza on the epidemic rise of morbidity in Russia in the 2006-2007 season

The paper gives the results of using ozeltamivir in patients with influenza during the epidemic upsurge of morbidity in Russia in the 2006-2007 season. Comparative analysis of nucteotide sequences of viral strains isolated from the patients taking ozeltamivir revealed no marker mutations determining the resistance to this chemical.

Authors
Kolobukhina L.V. 1 , Merkulova L.N. 1 , Burtseva Ye.I. 1 , Isayeva Ye.I. 1 , Shchelkanov M.Yu. 1 , Belyakova N.V. 1 , Grebennikova T.V. 1 , Polikushina O.E. 2 , Rotanov M. 3 , Malyshev N.A. 2 , Lvov D.K. 1
Issue number
4
Language
Russian
Pages
23-26
State
Published
Volume
53
Year
2008
Organizations
  • 1 D. I. Ivanovsky Institute of Virology, Russian Academy of Medical Sciences
  • 2 Infectious Clinical Hospital One
  • 3 P. Lumumba Russian University of Peoples' Friendship, Moscow, Russian Federation
Keywords
Chemotherapy; Influenza; Marker mutations; Ozeltamivir; Patient; Resistance
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