REACTIONS OF TETRAHYDROPYRIDO[4,5-D][1,2,4]TRIAZOLO[1,5-A]-PYRIMIDIN-4-ONES WITH ACTIVATED ALKYNES. SYNTHESIS OF [1,2,4]TRIAZOLO[1′,5′:1,2] PYRIMIDO[4,5-D]AZOCINES
Russian Chemical Bulletin. Vol. 61. 2012. P. 1603-1608
Tetrazolo[1,5-a][1,4]benzodiazepines were obtained by an efficient azide five-centered four-component Ugi reaction, which used ketones, sodium azide, ammonium chloride, and the corresponding isonitrile. Scope and limitations of this multi-component reaction were considered. © 2012 Springer Science+Business Media New York.