Comparative study of mass-spectrometric behavior of 2,6-diaryl-4-(oxo,oximino,amino)piperidines

The fragmentation of the investigated piperidine derivatives, which was confirmed by data from the high-resolution spectra, by the DADI spectra, and by the fragmentation of the deutero analogs, proceeds with cleavage of the piperidine ring and is due to the competitive distribution of the charge on the ring nitrogen atom and on the structural elements that contain functional groups and an aryl radical. The dependence of the mass spectra of 4-(oxo,oximino,amino)piperidines on the nature and position of the substituents in the ring, as well as on the character of the functional group in the 4 position of the ring, was investigated. © 1990 Plenum Publishing Corporation.