Hydrogenation of compounds containing an indolizine moiety and of 1-benzylisoquinoline over rhenium heptasulfide

It was shown by hydrogenation of 2,8-diphenylindolizine, benzo[2,3]indolizine, dibenzo[2,3;5,6]indolizine, dibenzo[ 2,3;7,8 ]indolizine, 1-benzylisoquinoline, and 2,3-dimethyl-6-ethyl-4-(4-nitrophenyl)pyridine over Re2S7 (250°C, {Mathematical expression} = 140 atm, 4 h) that the pyridine ring in benzoindolizines is hydrolyzed in preference to the pyrrole ring. Phenyl substituents at the indolizine do not prevent its complete reduction while alkyl substituents make reduction difficult. Annelation of the pyrrole and pyridine rings of indolizine lower the degree of its reduction; a nitro group is reduced to an amino group. © 1991 Plenum Publishing Corporation.

Authors
Khorkhe R.A.1, 2 , Soldatova S.A. 1, 2 , Soldatenkov A.T. 1, 2 , Ryashentseva M.A. 1, 2 , Prostakov N.S. 1, 2
Editors
-
Publisher
Kluwer Academic Publishers-Plenum Publishers
Number of issue
6
Language
English
Pages
1253-1256
Status
Published
Department
-
Number
-
Volume
40
Year
1991
Organizations
  • 1 N. D. Zelinskii Institute of Organic Chemistry, Academy of Sciences of the USSR, Moscow, Russian Federation
  • 2 P. Lumumba University of Friendship between Peoples, Moscow, Russian Federation
Keywords
-
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/1091/