Regulation of liver excretory function with antioxidants in toxic hepatitis

The effects of the antihelminthic agent chloxyl given to rabbits in different doses were compared with those of CCl4 on the excretory function of the liver. There was a similarity of the above agents in their inhibitory effects on hepatic excretory function. The hepatoprotective effect of the antioxidant sodium selenite was found to be more pronounced than that of vitamin E. The combination of the above antioxidants was most effective in normalizing the excretory function of the liver affected by CCl4 and chloxyl, revealing the potentiation of their effect.

Авторы
Vinogradova L.F. 1 , Mirzoyan Zh.A.
Редакторы
-
Издательство
-
Номер выпуска
5
Язык
Русский
Страницы
50-52
Статус
Опубликовано
Подразделение
-
DOI
-
Номер
-
Том
56
Год
1993
Организации
  • 1 Tsentral'naya NI Laboratoriya, Meditsinskij Fakul'tet, Ross. Universitet Druzhby Narodov, ul. Miklukho-Maklaya, 8, Moskva 117198, Russian Federation
Ключевые слова
alpha tocopherol; anthelmintic agent; antioxidant; carbon tetrachloride; hexachlorxylol; sodium selenite; animal experiment; article; controlled study; drug potentiation; liver function; liver protection; nonhuman; rabbit; toxic hepatitis
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/972/