EXPERIENCE OF HOSPITAL INITIATION OF SACUBITRIL/VALSARTAN IN A FEMALE PATIENT AFTER ACUTE DECOMPENSATED HEART FAILURE

The article discusses management of a female patient with chronic heart failure with reduced left ventricular ejection fraction after an episode of acute decompensation. Replacing an angiotensin-converting enzyme inhibitor with a representative of a new angiotensin receptor-neprilysin inhibitor class, sacubitril/valsartan, in the combination therapy allowed fast achievement and maintenance of the compensation state. The treatment was well tolerated and was not associated with clinically significant adverse effects.