Blood glucose, gas exchange, and hematological parameters in rats with experimental diabetes mellitus after carotid glomectomy

In glomectomized rats with denervated sinus carotid reflexogenic zones as compared with sham-operated controls, the diabetogenic action of streptozotocin was manifested by more pronounced changes in several hematological parameters, including marked elevation of blood glucose and reductions of oxygen consumption, the respiratory quotient, blood hemoglobin concentration, the hematocrit, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration. These findings attest that the carotid sinus receptors play an important functional role in producing the symptom complex of diabetes mellitus. © 1996, Plenum Publishing Corporation. All rights reserved.