Secondary prevention of acute disorders of brain-blood circulation in patients with asymptomatic vertebral arteries lesions

Almost 50% of patients who experience a stroke in the vertebrobasilar pool die within the first year after the stroke, and approximately 80% of patients experience disability. Additionally, the risk of re-stroke in these patients is significantly higher compared with damage to the carotid pool. Prospects for the restoration of brain functions and the ability to work in patients who have had a stroke in the vertebrobasilar pool remain very limited. In this connection, the problem of preventing cerebrovascular disorders in patients with chronic cerebral ischaemia with lesions of the vertebral arteries is currently extremely urgent. Particular attention should be paid to patients with asymptomatic chronic brain ischaemia. Possible reasons for the low efficiency of drug therapy and complications arising against this background are discussed. The feasibility of a more aggressive secondary prevention of cerebrovascular disorders, which includes endovascular interventions in combination with medical therapy, is demonstrated. © 2021 Meshalkin National Medical Research Center. All rights reserved.