International Journal of Trade and Global Markets.
Inderscience Publishers.
Том 14.
2021.
С. 548-558
Synthesis of novel C3-substituted 5,6-dihydropyrrolo[2,1-a]isoquinolines via a three-component domino reaction of 1-aroyl-3,4-dihydroisoquinolines, terminal alkynes and CH-acids under microwave irradiation in dry acetonitrile is described. The method developed enables the obtainment of highly functionalized compounds with pharmacophore groups, which are potentially biologically active. © 2021 Wiley-VHCA AG, Zurich, Switzerland