New oxidative reactions of 1,2,3,6-tetrahydropyridines: Imination, lactamination and decyclisation in the presence of potassium permanganate

A novel oxidative imination reaction of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine la by 4-nitroaniline/potassium permanganate has been found to occur yielding 2-(4-nitrophenyl)imino-1,2,5,6-tetrahydropyridine 4; in the absence of nitroaniline the shorter reaction time allows the reaction to be stopped at the unsaturated lactam 5 formation stage; the oxidation of 1a hydrochloride leads to 1-(N-formyl-N-methyl)amino-3-phenylpropan-2-one 6 via decyclisation-elimination steps, providing a new method for N-formyl-substituted aminoketone synthesis.

Авторы
Редакторы
-
Издательство
Royal Society of Chemistry
Номер выпуска
6
Язык
Английский
Страницы
243-244
Статус
Опубликовано
Подразделение
-
Номер
-
Том
7
Год
1997
Организации
  • 1 Russian Peoples Friendship University, 117198 Moscow, Russian Federation
Ключевые слова
-
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/756/