Comparative results of surgical, combined and comprehensive treatment of newly onset medulloblastoma in children

The authors present the outcomes of treatment of 107 patients with histologically verified diagnosis of medulloblastoma. Of these, 22 children were subjected only to surgical treatment, 25 – operative and radiotherapy, and 60 – polychemotherapy as a stage of a comprehensive or combined treatment. It was determined that survival of children with medulloblastoma was influenced by such factors as the presence of polychemotherapy and radiotherapy, a residual tumour following nonradical removal thereof, involvement of the brain stem into the tumour process, as well as tumour cells in the lumbal liquor. Carrying out ventriculoperitoneal by-pass decreases survival of patients with medulloblastoma. © 2002, Fund - Doctors, Innovations,Science for Children. All rights reserved.