Pharmacoeconomic assessment of dual bronchodilation therapy in patients with COPD

This study was aimed at clinical and economic assessment of feasibility of inclusion glycopyrronium bromide/indacaterol fixed combination in the State Program for providing necessary drugs to patients. Methods. This retrospective study was based on previously published clinical data. Change of economic burden was assessed using budget impact analysis. Cost-effectiveness was assessed using cost minimization analysis and lost opportunities analysis. Results. Switching COPD patients from free combination of long-acting bronchodilators (LABD) to glycopyrronium bromide/indacaterol fixed combination has led to 20.44% decrease in the economic burden. The 3-year cost saving of COPD therapy has reached RUB 2,416 bln. Conclusion. The results demonstrate pharmacoeconomic efficiency of glycopyrronium bromide/indacaterol fixed combination compared to the standard therapy of COPD. Inclusion of glycopyrronium bromide/indacaterol combination into the State Program for providing necessary drugs to COPD patients could be rational and ecomonically feasible. © 2018 Medical Education. All rights reserved.

Авторы
Zyryanov S.K. 1 , D'yakov I.N.2, 3
Редакторы
-
Журнал
Издательство
Medical Education
Номер выпуска
1
Язык
Русский
Страницы
61-68
Статус
Опубликовано
Подразделение
-
Номер
-
Том
28
Год
2018
Организации
  • 1 The Peoples' Friendship University of Russia (Medical University), ul. Miklukho-Maklaya 6, Moscow, 117198, Russian Federation
  • 2 I.I.Mechnikov, Federal Research Vaccine and Serum Institute, Russian Academy of Science, Malyy Kazennyy per. 5A, Moscow, 105064, Russian Federation
  • 3 Independent Non-commercial Organization “Research and Practical Center for Investigation of Issues of Rational Pharmacotherapy and Pharmacoeconomics”, ul. Aviamotornaya 50, build. 2, Moscow, 111024, Russian Federation
Ключевые слова
Budget impact analysis; COPD; Economic burden; Glycopyrronium bromide/indacaterol; Indacaterol; Long-acting bronchodilators; Tiotropium bromide
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/7290/