The aim of the research was to study the elemental and biochemical profiles of disabled athletes. Male athletes of sledge hockey club took part in the research. The control group consisted of men not going in for sports and working in hazardous industry. Methods. Biochemical blood characteristics were determined using a biochemical analyzer CS-T240 ("Dirui Industrial Co., Ltd", China). The study of hair trace elements content was carried out in the laboratory "Center for Biotic Medicine" (Moscow) using atomic-emission and mass spectrometry methods by means of Elan 9000 mass spectrometer and Optima 2000 V atomic-emission spectrometer. Data processing was carried out using the methods of variation statistics and by means of statistical package StatSoft STATISTICA 6.1.478 Russian, Enterprise Single. Results. Biochemical blood test of sledge hockey players showed higher level of glucose (p = 0.003), lower values of the common protein (p = 0.01), creatinine (p = 0.001), triglycerides (p = 0.005) and cholesterin (p = 0.005) in comparison with the control group. When comparing the elemental composition of hair of the sledge hockey players with the control group, higher content of Na by 2.3 times (p = 0.008), p by 2.5 times (p = 0.001) and P by 1.2 times (p = 0.001) in athletes was reveled. Fe level by 2.9 times (p = 0.001), I by 3.4 times (p = 0.001) and Ni by 2.8 times (p = 0.003) was lower, than in the control group. Besides, athletes had the lower level of Cr in 2.5 times (p = 0.0001) and V in 4.3 times (p = 0.0001). Conclusion. To maintain the health and athletic form of sledge hockey players, it is necessary to use specialized mineral complexes taking into account indicators of individual elemental status, biochemical profile and peculiarities of biogeochemical area. © 2018 Northern State Medical University. All rights reserved.