The characteristics of pregravid preparation of married couples with human papillomavirus and herpes simplex virus

Objective. To carry out a systems analysis of the data available in the current literature on the effect of herpes simplex virus (HSV) and human papillomavirus (HPV) on the reproductive health of a couple, on the ability to conceive, on the course of pregnancy, and on the efficacy of valacyclovir in pregravid preparation. Material and methods. The review includes the data of foreign and Russian articles published in the past 10 years and found in Pubmed on this topic. Results. The paper describes the role of viral infections in the occurrence of inflammatory diseases of the pelvic organs, leading to subfertility and infertility in both women and men, in the reduction of the efficiency of assisted reproductive technologies, and in the development of pregnancy complications. It presents data on the need for pregravid preparation using valacyclovir. Conclusion. Pregravid preparation should be done in couples with HPV/HSV infections. Valacyclovir has shown benefits in the treatment of HSV. © Bionika Media Ltd.