Drug-Related Carcinogenesis: Risk Factors and Approaches for Its Prevention

The review summarizes the data on the role of metabolic and repair systems in the mechanisms of therapy-related carcinogenesis and the effect of their polymorphism on the cancer development risk. The carcinogenic activity of different types of drugs, from the anticancer agents to analgesics, antipyretics, immunomodulators, hormones, natural remedies, and non-cancer drugs, is described. Possible approaches for the prevention of drug-related cancer induction at the initiation and promotion stages are discussed. © 2020, Pleiades Publishing, Ltd.

Авторы
Belitskiy G.A.1 , Kirsanov K.I. 1, 2 , Lesovaya E.A.1, 3 , Yakubovskaya M.G.1
Редакторы
-
Журнал
Издательство
-
Номер выпуска
-
Язык
Английский
Страницы
79-107
Статус
Опубликовано
Подразделение
-
Номер
-
Том
85
Год
2020
Организации
  • 1 Blokhin Russian Cancer Research Center, Ministry of Health of Russian Federation, Moscow, 115478, Russian Federation
  • 2 Peoples’ Friendship University of Russia, Moscow, 117198, Russian Federation
  • 3 Pavlov Ryazan State Medical University, Ryazan, 390026, Russian Federation
Ключевые слова
cancer prevention; secondary tumors; therapy-related carcinogenesis
Дата создания
02.11.2020
Дата изменения
02.11.2020
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/65547/