Evaluation of conservative therapy outcomes in patients with decompensated lower limb ischemia within one-year follow-up period using wifi classification system

Objective. To assess an efficacy of prostaglandin E1 (PGE1) in complex therapy of inoperable critical lower limb ischemia within one-year follow up period using WIfI classification system. Material and methods. A retrospective, multiple-center trial included 109 patients (60 men and 49 women). Mean age was 70±7,3 years. Patients were divided into 2 groups. Group 1 (n=58) — standard therapy without PGE1, group 2 (n=51) — standard therapy with PGE1. Statistical analysis included chi-square test with Fisher’s exact test, log-rank test. Results. There were no significant between-group differences in all endpoints within one-year follow up period. Conclusion. PGE1 in complex conservative treatment does not influence major amputation rate, amputation-free survival and overall mortality in patients with critical lower limb ischemia for all WIfI combinations (130, 131, 230, 231) within one-year follow up period. © 2020, Media Sphera Publishing Group. All rights reserved.

Авторы
Chervyakov Y.V.1 , Kha K.N. 2 , Klimov A.E. 2 , Gavrilenko A.V. 3, 4
Номер выпуска
4
Язык
Русский
Страницы
347-354
Статус
Опубликовано
Том
13
Год
2020
Организации
  • 1 Yaroslavl State Medical University, Yaroslavl, Russian Federation
  • 2 Peoples’ Friendship University of Russia, Moscow, Russian Federation
  • 3 Petrovsky Russian Research Center of Surgery, Moscow, Russian Federation
  • 4 Sechenov First Moscow State Medical University, Moscow, Russian Federation
Ключевые слова
Conservative treatment; Critical lower limb ischemia; PGE1; WIfI classification
Дата создания
02.11.2020
Дата изменения
02.11.2020
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/65485/
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