About the role of environmental factors in carcinogenesis

There were found out the connections of the activity of the Sun and smoke of forest fires with the incidence of various forms of benign and malignant neoplasms in the population of young children 0-4 years old, in Khabarovsk Region, Russia. Thus, it was determined that so-called "sporadic" fluctuations in the incidence of neoplasms in the child population are not random. They are caused by long multi-year cycles of changes in the complex of environmental factors. The authors identified this phenomenon as "Alternative oncogenesis", meaning by it the predominant occurrence of various forms of neoplasms in a certain period of time due to a change in the parameters of the complex of environmental factors. A proposed hypothesis is: ecologically linked oxidative stress as a cause of the epigenomic modulation leading to an imbalance between semaphorins and integrins that brings to oncogenesis. © The Authors, published by EDP Sciences, 2020.

Авторы
Сборник материалов конференции
Издательство
EDP Sciences
Язык
Английский
Статус
Опубликовано
Номер
04003
Том
169
Год
2020
Организации
  • 1 Far Eastern State Medical University, Khabarovsk, Russian Federation
  • 2 Peoples' Friendship University of Russia (RUDN University), Faculty of Ecology, 6 MiklukhoMaklaya St, Moscow, 117198, Russian Federation
Ключевые слова
Deforestation; Ecology; Planning; Smoke; Sustainable development; Tumors; Environmental factors; Forest fires; Integrins; Oncogenesis; Young children; Environmental management
Дата создания
02.11.2020
Дата изменения
02.11.2020
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/64739/
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