One-Pot Synthesis of Thieno[2,3-b]pyridine and Pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine Derivatives

Abstract: 2-Acyl-4,5,6-trialkyl-3-aminothieno[2,3-b]pyridines, 8′-ethyl-7′,9′-dimethyl-1′H-spiro[cyclohexane-1,2′-pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin]-4′(3′H)-one, and 7,8,9-trimethylpyrido[3′,2′:4,5]thieno[3,2-d]pyrimidin-4-amine have been synthesized by one-pot three-component condensation of 3-methyl(ethyl)pentane-2,4-diones with cyanothioacetamide and α-halocarbonyl compounds, cyclohexanone, or formamide. The structures of some of the synthesized thieno[2,3-b]pyridine derivatives have been studied by X-ray analysis. © 2020, Pleiades Publishing, Ltd.

Авторы
Dyachenko I.V.1 , Dyachenko V.D.1 , Dorovatovsky P.V.2 , Khrustalev V.N. 3, 4 , Nenajdenko V.G. 5
Номер выпуска
6
Язык
Английский
Страницы
974-982
Статус
Опубликовано
Том
56
Год
2020
Организации
  • 1 Taras Shevchenko Lugansk National University, Lugansk, 91011, Ukraine
  • 2 Kurchatov Institute National Research Center, Moscow, 123182, Russian Federation
  • 3 Peoples’ Friendship University of Russia, Moscow, 117198, Russian Federation
  • 4 Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, 119991, Russian Federation
  • 5 Faculty of Chemistry, Moscow State University, Moscow, 119991, Russian Federation
Ключевые слова
3-methyl(ethyl)pentane-2,4-diones; cyanothioacetamide; cyclohexanone; formamide; pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidines; thieno[2,3-b]pyridines; X-ray analysis; α-halocarbonyl compounds
Дата создания
02.11.2020
Дата изменения
02.11.2020
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/64696/