Drug-related crime is a very special kind of the professional criminal activity of the highly organized and well-conspired narco-Trafficking groups with international contacts, corrupted relations and officials and dealing with the drug trafficking for the systematical maximizing of the income. A look will be taken at the factors and the special features of the drug-related crimes in China. And at the factors and the special features of the drug-related crimes that happen in Japan. It is a well-known fact that the efficiency of the Asia Pacific region (APR) legislation on criminal offenses is impressive, wich includes its application in the drug-related crime spectrum. China, Japan and other countries of APR are the countries that still widely apply the institution of the death penalty and the life imprisonment, on the other hand the European countries, including Russia, harmonize the legislation of the countries trying to change their politics and use mainly the humane forms of punishment. Despite the fact that the Asia Pacific region criminal legislation regularly implements the reforms aimed at socio-economic and political development of the country, drug-related crimes are still at a high level that's needs to be lowered quitea bit, and the number of these crimes continues to grow and it poses a very serious threat not only to APR but also to other countries of the whole world. There should be a promotion of the healthy lifestyle including physical training and sports aimed at the formation of negative attitude to drug addiction in society should be primarily oriented to the younger generations. The Reforms in the legislative activaty in the sphere of the drug-related crime scene should be implemented regularly and not only within the country but also comprehensively on a worldwide basis with consideration for the specific features that legislation in neighboring region will have.