Underdevelopment of the market infrastructure, lack of financial resources, administrative barriers, unsettled lending problems, disorder of land relations, high level of migration of the rural population, especially youth and other factors acted as the main constraints to economic growth and social transformations in the agro-industrial complex. At the same time, the state practically avoided solving these problems on the wave of the ideology of market self-regulation of the economy. The size of budgetary aid to agrarians decreased, the volumes of crediting and investments did not correspond to real needs, and the conducted price policy proved destructive for the majority of agricultural organizations. All this and other negative factors led to significant losses in the complex. Recently, state authorities began to consider the agrarian sector of the economy and its development issues as priorities of state policy. In particular, a number of federal and regional programs were adopted to resolve the accumulated economic and social problems of the agro-industrial complex and rural areas. In addition, the situation of agrarians has recently become more complicated due to the accession of our country to the World Trade Organization, as well as the introduction of sanctions by a number of countries against Russia in connection with its actions in Ukraine, and therefore the problem of import substitution of food products has acquired particular relevance. In these conditions, it is important to realize that the country's food independence is impossible without developing its own innovations and own science, the agribusiness sector needs modernization and additional investment infusions.