Synthesis of Functionalized Partially Hydrogenated Quinolines by a Stork Reaction - Intramolecular Transamination - Alkylation Tandem Protocol

A Stork reaction — intramolecular transamination — alkylation tandem protocol was used to synthesize functionalized partially hydrogenated quinolines. The molecular and crystal structures of 5-(4-methoxyphenyl)-8,8-dimethyl-6-oxo-2,5,6,7,8,9-hexahydro-1H-thiazolo[3,2-a]quinoline-4-carbonitrile, 9-allyl-3-amino-7,7-dimethyl-5-oxo-4-phenyl-4,5,6,7,8,9-hexahydrothieno[2,3-b]quinoline-2-carbonitrile, and 3-amino-4-(2,5-dimethoxyphenyl)-N-phenyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide were studied by X-ray diffraction analysis.

Авторы
Dyachenko I.V.1 , Kalashnik I.N.1 , Dyachenko V.D.1 , Dorovatovskii P.V. 2 , Khrustalev V.N. 2, 3 , Nenaidento V.G.4
Номер выпуска
8
Язык
Английский
Страницы
1177-1188
Статус
Опубликовано
Том
55
Год
2019
Организации
  • 1 Taras Shevchenko Lugansk National University
  • 2 Kurchatov Institute National Research Center
  • 3 Peoples’ Friendship University of Russia (RUDN University)
  • 4 Lomonosov Moscow State University
Ключевые слова
alkylation; intramolecular transamination; Partially hydrogenated quinolines; Stork reaction; x-ray diffraction analysis; [3,3]-Sigmatropic rearrangement
Дата создания
20.02.2020
Дата изменения
20.02.2020
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/59542/