Comparison of topical oxybuprocaine and intravenous fentanyl in pediatric strabismus surgery

Purpose: To compare the outcomes such as postoperative nausea/vomiting, analgesic requirements, and hospital stay following the use of topical oxybuprocaine hydrochloride 0.4% or intravenous (IV) fentanyl in children undergoing strabismus surgery. Methods: This was a prospective cohort study. Children operated under general anesthesia for strabismus were given topical oxybuprocaine hydrochloride 0.4% (Group T) and IV fentanyl (Group F) before surgery. The episodes of nausea/vomiting, pain score, requirement of additional analgesia during postoperative period, and duration of hospital stay were compared in two groups. Results: There were 47 children in Group T and 59 children in Group F. The median pain score in two groups were 2.38 (25% quartile; 2.0) and 3.00 (25% quartile; 3.00), respectively. The difference was significant (K W P < 0.03). The episodes of nausea/vomiting in two groups were in 2 and 6 children in Group T and Group F, respectively. The median hospital stay of children of Group T and Group F were 242 and 285 min, respectively. The difference was not statistically significant (P = 0.22). Conclusions: Using intraoperative topical oxybuprocaine drops, one can achieve better analgesic outcomes and reduce risk of nausea and vomiting compared to intravenous opioid analgesics and therefore, the hospital stay could also be marginally reduced. © 2017 Saudi Journal of Anesthesia | Published by Wolters Kluwer - Medknow.

Авторы
Yousafzai I.1 , Zahoor A.1 , Andrey B. 2 , Ahmad N.1
Издательство
Medknow Publications
Номер выпуска
1
Язык
Английский
Страницы
67-71
Статус
Опубликовано
Том
11
Год
2017
Организации
  • 1 Department of Anesthesia, King Khaled Eye Specialist Hospital, P. O. Box 7191, Riyadh, 11462, Saudi Arabia
  • 2 Department of Anesthesiology and Reanimatology, Russian People's Friendship University, State Prize Laureate of USSR, Moscow, Russian Federation
Ключевые слова
Analgesia; pain score; strabismus
Дата создания
19.10.2018
Дата изменения
19.10.2018
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/5893/
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