Interactions of some intracellular Hyalomma asiaticum pathogens in organism

Aim: The aim of this study was to study the interaction of intracellular pathogens of tick-borne encephalitis (TBE) and salmonella in Hyalomma asiaticum tick body during the bloodsucking of imago and nymphs on laboratory animals with viremia and bacteremia. With a simultaneous infection from H. asiaticum ticks by two intracellular pathogens (CE and salmonella virus), the virus titer decreases after 30-40 days, and then, the ticks die. Materials and Methods: The study was conducted on the ticks of a laboratory line, free from pathogenic flora. Tick encephalitis virus was used to infect ticks with the "Sofin" strain and the bacterial culture Salmonella typhimurium LT-2. Results: During an infection of nymphs, H. asiaticum virus persisted in their body for the entire observed period, both at the infection of nymphs with a mixed infection and at the infection with TBE virus. Salmonella persisted in the body of sexually mature H. asiaticum ticks with a mixed infection up to 12 days. Conclusions: With a mixed infection of ticks by two infection pathogens at the same time (TBE and salmonella virus), the inhibition of both TBE and salmonella virus growth and development takes place. © 2019 JPR Solutions. All rights reserved.

Журнал
Издательство
JPR Solutions
Номер выпуска
3
Язык
Английский
Страницы
517-520
Статус
Опубликовано
Том
11
Год
2019
Организации
  • 1 Fedepal State Budgetary Institution, National Research Center for Epidemiology and Microbiology n.a. honorary academician N.F. Gamaleya, Ministry of Health of the Russian Federation, 18 Gamaleya Street, Moscow, 123098, Russian Federation
  • 2 Department of Medical Institute, Peoples' Friendship University of Russia, RUDN University, Moscow, 117198, Russian Federation
Ключевые слова
Borrelia; Hyalomma asiaticum; Salmonella; Tick-borne encephalitis
Дата создания
10.02.2020
Дата изменения
10.02.2020
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/56433/