Synthesis of Functionalized Bicyclic Compounds Based on 2-(1-Arylethylidene)malononitriles

New tetrahydroisoquinoline-5,7-dicarbonitrile derivatives have been synthesized by piperazine hydrate-catalyzed reaction of acetoacetanilide with 2-(1-arylethylidene)malononitriles (Knoevenagel condensation products of acetophenones and malononitrile) in aqueous ethanol at room temperature. The product structure was confirmed by NMR spectra and X-ray analysis of 1,6-diamino-4a-methyl-3-oxo-2,8-diphenyl-2,3,4,4a-tetrahydroisoquinoline-5,7-dicarbonitrile. © 2019, Pleiades Publishing, Ltd.

Авторы
Naghiyev F.N.1 , Mamedov I.G.1 , Asadov K.A.1 , Dorovatovskii P.V. 2 , Khrustalev V.N. 3, 4 , Maharramov A.M. 1
Номер выпуска
12
Язык
Английский
Страницы
1967-1970
Статус
Опубликовано
Том
55
Год
2019
Организации
  • 1 Baku State University, Baku, 1148, Azerbaijan
  • 2 Kurchatov Institute National Research Center, Moscow, 123182, Russian Federation
  • 3 People’s Friendship University of Russia, Moscow, 117198, Russian Federation
  • 4 Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, 119991, Russian Federation
Ключевые слова
2-(1-arylethylidene)malononitriles; acetoacetanilide; NMR; tetrahydroisoquinoline-5,7-dicarbonitriles; X-ray analysis
Дата создания
10.02.2020
Дата изменения
10.02.2020
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/56307/