This study aims to evaluate the effectiveness of quantitative indicators in assessing the state of functional reserves of the body in patients with type 2 diabetes mellitus (DM 2) and metabolic syndrome (MS) and to develop the individual programs at the stages of medical rehabilitation and monitoring the adequacy and quality of therapy. The study comprised 124 individuals, 92 of them were diagnosed diabetes mellitus type 2 and 32 patients with metabolic syndrome. The two important aspects of problems has been envisaged in this investigation; 1- the effect of the preserved functional reserves of the body on the course and progression of systemic diseases (Diabetes mellitus); 2- the effectiveness of using the qualitative assessment method of the state of functional reserves of the body (an indicator of adaptive compliance) to predict the effectiveness and current monitoring of therapy. The assessment of the state of functional reserves with adaptation consistency criteria (ACC) in examined diabetic patients illustrated high and satisfactory rehabilitation potential. At the second stage of the study, the criteria for patient's distribution into groups was the preserved functional reserves of the body according to ACC with the development of personalized rehabilitation programs at the outpatient stage. The method allows carrying out as control of treatment and making a forecast. © 2019 Association for Computing Machinery.