Synthesis of Functionalized Partially Hydrogenated Quinolines by a Stork Reaction — Intramolecular Transamination — Alkylation Tandem Protocol

A Stork reaction — intramolecular transamination — alkylation tandem protocol was used to synthesize functionalized partially hydrogenated quinolines. The molecular and crystal structures of 5-(4-methoxyphenyl)-8,8-dimethyl-6-oxo-2,5,6,7,8,9-hexahydro-1H-thiazolo[3,2-a]quinoline-4-carbonitrile, 9-allyl-3-amino-7,7-dimethyl-5-oxo-4-phenyl-4,5,6,7,8,9-hexahydrothieno[2,3-b]quinoline-2-carbonitrile, and 3-amino-4-(2,5-dimethoxyphenyl)-N-phenyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide were studied by X-ray diffraction analysis. © 2019, Pleiades Publishing, Ltd.

Авторы
Dyachenko I.V.1 , Kalashnik I.N.1 , Dyachenko V.D.1 , Dorovatovskii P.V. 2 , Khrustalev V.N. 2, 3 , Nenaidento V.G.4
Номер выпуска
8
Язык
Английский
Страницы
1177-1188
Статус
Опубликовано
Том
55
Год
2019
Организации
  • 1 Taras Shevchenko Lugansk National University, ul. Oboronnaya 2, Lugansk, 91011, Ukraine
  • 2 Kurchatov Institute National Research Center, ul. Akademika Kurchatova 1, Moscow, 123182, Russian Federation
  • 3 Peoples’ Friendship University of Russia (RUDN University), ul. Miklukho-Maklaya 6, Moscow, 117198, Russian Federation
  • 4 Lomonosov Moscow State University, ul. Leninskie Gory 1, Stroenie 3, Moscow, 119991, Russian Federation
Ключевые слова
alkylation; intramolecular transamination; partially hydrogenated quinolines; Stork reaction; X-ray diffraction analysis; [3,3]-sigmatropic rearrangement
Дата создания
24.12.2019
Дата изменения
24.12.2019
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/55125/