Studies on pesticide load were carried out. The number and the classes of toxic chemicals used in the republic and their ranking by hazard class and toxicological stress are given. Pesticide-contaminated zones of Dagestan were identified. The dependence of the prevalence of dentofacial anomalies and the prognosis of the incidence of the population living in the zones of environmental trouble have been revealed. © The Authors, published by EDP Sciences, 2019.